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What are the effects of CBD on Parkinson's disease?

What are the effects of CBD on Parkinson's disease?


Parkinson's disease was discovered in 1817. It is a neurodegenerative disease that occurs as a result of the progressive death of neurons in the area of the brain called the substantia nigra, and the decrease of dopamine levels in the synapses.

In France, approximately 200,000 people are affected by the disease. Each year, 25,000 additional cases are detected, particularly in people aged 55 to 65. However, the disease sometimes manifests itself earlier.


Parkinson's disease is characterized by tremors, muscle stiffness and motor problems.

Although Parkinson's disease cannot be cured, the progression of the disease can be delayed by carefully orchestrated changes in diet, lifestyle and the use of medications and supplements.


To date, there is no cure for Parkinson's disease, as medicine can only reduce the intensity of symptoms and delay the development of the disease. An example with CBD.


5 positive effects of CBD on Parkinson's disease!


In the context of Parkinson's disease, there is a non-exhaustive list of 5 effects to discover below, which improve the quality of life of Parkinson's patients.


Anti-inflammatory and pain-relieving effects


CBD is a powerful anti-inflammatory and pain reliever whose effects have already been found on inflammatory diseases like multiple sclerosis and painful diseases like migraine through numerous studies. A small-scale study on Parkinson's patients has also been conducted and shows the positive effects of CBD and THC.


A six-week study in Brazil was conducted on 21 Parkinson's patients with comorbidities (dementia and psychiatric disorders). The panel was divided into three groups. The first group received 330mg of CBD, per day, in capsule form. The second group received 75mg of CBD, again in capsule form, while the last group received a placebo. As a result, motor symptoms and pain were reduced in the first two groups that received CBD.

Reduction of tremors


Some of the most common symptoms of Parkinson's disease are tremors or uncontrolled muscle movements. Drug treatments do not improve or even worsen this symptom.


A scientific study conducted in 1986 suggests that CBD could help relieve these muscle movements. More recent studies must be carried out to confirm this significant benefit which drastically improves the quality of life of patients.


Reduce depression and psychotic disorders


People with Parkinson's disease are subject to anxiety disorders that can lead to depression or even psychotic episodes, especially if patients are not well accompanied and isolated from social events. Indeed, it is estimated that 50% of patients suffer from this. CBD can reduce these disorders through its anti-inflammatory, pain-relieving and soothing effects.


Improves sleep quality


One of the most well-known natural benefits appreciated by CBD users is the improvement of sleep. Scientific studies are clear on this subject, Parkinson's patients can benefit from CBD to sleep better, without side effects.


Support a better quality of life


Finally, a study confirms that the controlled consumption of CBD by Parkinson's patients supports the improvement of their quality of life. More research on this topic needs to be done, however, to confirm the precise effects on different aspects of patients' lives.

Finally, CBD is likely to protect neurons and slow down their destruction. This is very interesting in the context of Parkinson's since it is the cause of the disease. The CBD would have indeed, according to several preclinical studies like this one, neuro protective properties. CBD acts on the inflammatory process by inhibiting the production of cytokines and the release of glutamates and by reducing oxidative stress. Thus, the deterioration of cells is slowed down and the renewal of neurons is promoted. Thanks to this protective function, CBD improves the metabolic activity of the brain, which improves motor and cognitive performance.

CBD is a product that supports this quest by bringing therapeutic properties that can diminish the side effects of existing treatments and soothe or even fight against very restrictive psychological disorders.

However, Parkinson's patients should not self-administer CBD products alongside their medical treatment. It is highly recommended to buy quality products and to consult one's doctor beforehand in order to define the dosage.


CBD oil would improve the life of patients by acting on other effects of the disease


It has been shown that CBD oil is also beneficial against Parkinson's disease. It acts on some of its motor symptoms and limits the side effects of drugs by acting on other effects of the disease.


The intake is done in sublingual: once or twice a day, we put one or two drops under the tongue, away from meals or on an empty stomach, as for homeopathy. There is no risk of overdosing, and very few side effects have been observed (some patients may have digestive problems during the first few doses, but nothing restrictive). 


The general advice is to start with a small dosage. The effects are fully established after 10 days, but relief can be obtained from the first dose, particularly for pain and sleep.


Depending on the symptoms, other treatments can be considered, such as CBD infusions before bedtime to regulate the symptoms of Parkinson's on sleep (which tend to shorten the nights). CBD has a rapid calming effect and helps to stabilize sleep cycles and REM sleep), it helps to stay asleep. Some users also put two drops in a spoonful of honey before bed. Unlike other sleep treatments, it does not cause drowsiness the next day.

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